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Dept. of Neuroscience & Regenerative Medicine
The Goldstein Lab
Dept. of Neuroscience & Regenerative Medicine
The Goldstein Lab
1201 Goss Lane - GE2017Augusta UniversityAugusta, GA 30912
Phone: (706) 723-4391
Email: egoldstein@augusta.edu
Over 10% of infants are born preterm.
Premature Infants
White Matter Injuries
Oligodendrocytes Lineage Cells
In Vivo Models
Transcriptional Regulation
Myelin, which quickens signal conduction in the brain, are abnormally formed, due to oxidative stress to the cells that produce it. This abnormal myelin formation is what we call white matter injury (WMI).
The oxygen-reliant cells impacted by premature birth are oligodendrocytes. Current research indicates that premature birth delays maturation, causing WMI. This is the cell line we investigate in our lab.
In vivo models discovered that environmental enrichment (EE), such as the introduction of toys, social interaction, and exercise, offset WMI in premature (low-oxygen) models
Our lab is currently researching the transcriptional modifications that might explain the impacts of EE on premature infants.
Dept. of Neuroscience & Regenerative Medicine
1201 Goss Lane - GE2017Augusta UniversityAugusta, GA 30912
Phone: (706) 723-4391
Email: egoldstein@augusta.edu
